3-(6-Methoxy-cyclohex-1-enyl)-1H-indole → 3-(2-Methoxy-cyclohexyl)-1H-indole

Beteiligte Stoffe

Reaktionsschritte

Treat 3-(6-methoxy-cyclohex-1-enyl)-1H-indole (200 mg, 0.879 mmol) with 10% Pd/C (40 mg) in EtOAc under atmospheric hydrogenation conditions for 1.5 hours. Filter resulting solution over Celite to remove catalyst. Concentrate crude on rotovap and purify on silica gel chromatography to give 3-(2-Methoxy-cyclohexyl)-1H-indole (127 mg, 63% yield). Mass Spectrum (m/e): 230.03 (MH+), 228.14 (M−).

Herkunft & Nachweise