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HRID1178911

反应详情

EQUATION

反应方程式

HRID 1178911 的结构方程式

REACTANTS

反应物

3
结构：CCCC[N+](CCCC)(CCCC)CCCC.[F-]
HCID2724141

Tetra-n-butylammonium fluoride

C16H36FN

结构：c1ccc2c(N3CCOCC3)c[nH]c2c1
HCID12530833

未命名化合物

结构：CC(C)[Si](C(C)C)(C(C)C)n1cc(N2CCCCC2)c2ccccc21
HCID58974986

未命名化合物

PRODUCTS

生成物

1
结构：c1ccc2c(N3CCCCC3)c[nH]c2c1
HCID87092

3-(Piperidin-1-yl)-1H-indole

C13H16N2

收率 71.3%

PROCEDURE

实验过程

Following a method similar to 3-morpholin-4-yl-1H-indole using 3-Piperidin-1-yl-1-triisopropylsilanyl-1H-indole (0.30 g, 0.84 mmol) and 1N solution of tetrabutylammonium fluoride (1.30 mL). Purify by flash chromatography using 20 to 50% of EtOAc in hexanes to give the title compound (0.12 g 71%). MS (ES) 201.1 (M+1)+.

WORKUP

后处理

  1. customPurify by flash chromatography