3-Methyl-2-thiophenecarboxaldehyde → HCID 10074271, compound

HRID 1179334Notes

Reaction equation

HRID 1179334 reaction equation
[Br:1][C:2]1[CH:23]=[CH:22][C:5]2[N:6]([CH:10]3[CH2:15][CH2:14][N:13]([CH:16]4[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]4)[CH2:12][CH2:11]3)[C:7](=[O:9])[NH:8][C:4]=2[CH:3]=1.[CH3:24][C:25]1[CH:29]=[CH:28][S:27][C:26]=1[CH:30]=O>>[Br:1][C:2]1[CH:23]=[CH:22][C:5]2[N:6]([CH:10]3[CH2:15][CH2:14][N:13]([CH:16]4[CH2:17][CH2:18][N:19]([CH2:30][C:26]5[S:27][CH:28]=[CH:29][C:25]=5[CH3:24])[CH2:20][CH2:21]4)[CH2:12][CH2:11]3)[C:7](=[O:9])[NH:8][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 799113-Methyl-2-thiophenecarboxaldehydeHCID 69458250HCID 69458250, compound

Product 1

HCID 10074271HCID 10074271, compound

Procedure

The title compound was prepared according to the procedure described in Example 18, using 5-bromo-1-[1-(piperidin-4-yl)piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one and 3-methyl-2-thenaldehyde.

Sources & evidence

ORD record
ord-bf07dcd6071f484ca4800e97845ab098
Source dataset
uspto-grants-2007_10
Patent number
US07279490B2

Reaction notes

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