4-Fluoro-3-methylbenzaldehyde → 3-Methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzaldehyde

HRID 1179390Notes

Reaction equation

HRID 1179390 reaction equation
[N:1]1([CH2:6][CH:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.F[C:14]1[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][C:15]=1[CH3:22]>>[CH3:22][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][C:14]=1[N:10]1[CH2:11][CH2:12][CH:7]([CH2:6][N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)[CH2:8][CH2:9]1)[CH:18]=[O:19]

Participants

3

Reactant 2

HCID 27348744-Fluoro-3-methylbenzaldehydeHCID 167683474-(Pyrrolidin-1-ylmethyl)piperidine

Product 1

HCID 589780393-Methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzaldehyde

Procedure

Prepared from the product of Example 4 and 4-fluoro-3-methyl-benzaldehyde.

Sources & evidence

ORD record
ord-75bc3cf0abce4082822bcf3f285252e1
Source dataset
uspto-grants-2007_10
Patent number
US07279491B2

Reaction notes

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