HCID 10480667, compound → 571141-49-6

Participants

Reaction Steps

To the solution of the nitro compound (521 mg, 1.07 mmol) prepared from example 3 in methanol (3 mL) was added 10% Pd/C. The mixture was hydrogenated at room temperature under 3 atmosphere pressure of H2 for 12 hours, and filtered through a pad of Celite. The filtrate was concentrated, and the residue was purified by silica gel column chromatography (5% methanol in dichloromethane) to afford the title compound (368 mg, 75%).

Provenance & Evidence