Acetyl chloride → HCID 86608402, compound

HRID 1179520Notes

Reaction equation

HRID 1179520 reaction equation
COC[O:4][C:5]1[C:10]([C:11]([CH3:14])([CH3:13])[CH3:12])=[CH:9][C:8]([CH3:15])=[CH:7][C:6]=1[P:16]([C:21]1[CH:26]=[C:25]([CH3:27])[CH:24]=[C:23]([C:28]([CH3:31])([CH3:30])[CH3:29])[C:22]=1[O:32]COC)[C:17]([CH3:20])([CH3:19])[CH3:18].C(Cl)(=O)C>C(OCC)(=O)C.CO>[OH:32][C:22]1[C:23]([C:28]([CH3:30])([CH3:31])[CH3:29])=[CH:24][C:25]([CH3:27])=[CH:26][C:21]=1[P:16]([C:6]1[CH:7]=[C:8]([CH3:15])[CH:9]=[C:10]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:5]=1[OH:4])[C:17]([CH3:18])([CH3:19])[CH3:20]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 69501159HCID 69501159, compound

Product 1

HCID 86608402HCID 86608402, compound

Reagents, catalysts & solvents 1

HCID 21584119Ethylacetate methanolSolvent

Procedure

To an ethyl acetate/methanol=1/1 solution (60 mL) of bis(2-methoxymethoxy-3-tert-butyl-5-methylphenyl)(tert-butyl)phosphine (1.01 g, 2 mmol) was added acetyl chloride (0.79 g, 10.0 mmol) at room temperature, and the mixture was stirred at room temperature for 15 hours. The solvent was distilled off under reduced pressure to quantitatively obtain bis(2-hydroxy-3-tert-butyl-5-methylphenyl)(tert-butyl)phosphine as a pale yellow solid.

Workup

  1. distillationThe solvent was distilled off under reduced pressure to quantitatively obtain bis(2-hydroxy-3-tert-butyl-5-methylphenyl)(tert-butyl)phosphine as a pale yellow solid

Sources & evidence

ORD record
ord-bdbebc40155649718a6fbbdac5f07d88
Source dataset
uspto-grants-2007_10
Patent number
US07279537B2

Reaction notes

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