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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1179536Generated: October 26, 2026

3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline → 3-{2-[4-(7-Chloro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline

https://huagongshe.com/reaction/1179536

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
Reactant7-Chloro-2-methyl-5-{4-[2-(3-nitrophenyl)ethyl]-1-piperazinyl}quinolineHCID 57444276—
Product3-{2-[4-(7-Chloro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 5744430992%

Reaction Steps

The title compound was prepared in 92% yield using a similar procedure to description D6 starting from 7-Chloro-2-methyl-5-{4-[2-(3nitrophenyl)ethyl]-1-piperazinyl}quinoline (D17).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07279481B2
Source datasetuspto-grants-2007_10
ORD IDord-c8bcd66491ef4911970d871b559ffd4f
Source noteuspto-grants-2007_10