HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3-Thiadiazole-4-carboxylic acid → N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1,2,3-thiadiazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3-Thiadiazole-4-carboxylic acid | HCID 351418 | — |
| Reactant | 3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 49852105 | — |
| Product | N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1,2,3-thiadiazole-4-carboxamide | HCID 57478293 | 75% |
Reaction Steps
The title compound was prepared in 75% yield according to the general procedure for the preparation of the amides (Method C) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 1,2,3-thiadiazole4-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279481B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-e295d7ede5bc401ba425f06d8404817e |
| Source note | uspto-grants-2007_10 |