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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1179561Generated: October 31, 2026

Ethyl chloroformate → Ethyl (3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate dihydrochloride

https://huagongshe.com/reaction/1179561

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl chloroformateHCID 10928—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
ProductEthyl (3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate dihydrochlorideHCID 4985116479%

Reaction Steps

The title compound was prepared in 79% yield according to the general procedure for the preparation of carbamates (Method D) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and ethyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07279481B2
Source datasetuspto-grants-2007_10
ORD IDord-6fa63aa03bde45ef8b6749c6a4d908a6
Source noteuspto-grants-2007_10