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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1179562Generated: October 27, 2026

Propyl chloroformate → Propyl (3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate dihydrochloride

https://huagongshe.com/reaction/1179562

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropyl chloroformateHCID 7998—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
ProductPropyl (3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate dihydrochlorideHCID 8660843978%

Reaction Steps

The title compound was prepared in 78% yield according to the general procedure for the preparation of carbamates (Method D) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and propyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07279481B2
Source datasetuspto-grants-2007_10
ORD IDord-5ecaedfdf3344a6bb3f68bc28ccecbd9
Source noteuspto-grants-2007_10