HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperazine, (S)- → 2-Methyl-5-[(3S)-3-methyl-1-piperazinyl]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperazine, (S)- | HCID 2734219 | — |
| Reactant | 2-Methylquinolin-5-yl trifluoromethanesulfonate | HCID 49851899 | — |
| Product | 2-Methyl-5-[(3S)-3-methyl-1-piperazinyl]quinoline | HCID 57444341 | 27% |
Reaction Steps
The title compound was prepared in 27% yield using a similar procedure to Example 127 starting from (2S)-2-methylpiperazine and 2-methyl-5-quinolinyl trifluoromethanesulfonate (D1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279481B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-5653bdfd5bae47038b58ba6afafa573e |
| Source note | uspto-grants-2007_10 |