3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline → N-(3-{3-[4-(2-Methyl-quinolin-5-yl)-piperazin-1-yl]-propyl}-phenyl)-methanesulfonamide

HRID 1179653Notes

Reaction equation

HRID 1179653 reaction equation
O=[CH:2][CH2:3][CH2:4][C:5]1[CH:6]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:9][CH:10]=1.[CH3:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][C:23]=2[N:27]2[CH2:32][CH2:31][N:30](CCC3C=C(C=CC=3)N)[CH2:29][CH2:28]2)[N:18]=1>>[CH3:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][C:23]=2[N:27]2[CH2:32][CH2:31][N:30]([CH2:2][CH2:3][CH2:4][C:5]3[CH:6]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:9][CH:10]=3)[CH2:29][CH2:28]2)[N:18]=1

Participants

3

Reactant 2

HCID 498521053-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 57444373N-[3-(3-Oxo-propyl)-phenyl]-methanesulfonamide

Product 1

HCID 57444372N-(3-{3-[4-(2-Methyl-quinolin-5-yl)-piperazin-1-yl]-propyl}-phenyl)-methanesulfonamide

Procedure

The title compound was prepared from N-[3-(3-oxo-propyl)-phenyl]-methanesulfonamide and of 2-methyl-5-(1-piperazinyl)quinoline (D3) according to the methods in Description 4 and Description 5.

Sources & evidence

ORD record
ord-e23afaa4991c4e8fac7bfe956d1dd602
Source dataset
uspto-grants-2007_10
Patent number
US07279481B2

Reaction notes

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