4-(Trifluoromethyl)benzoyl chloride → HCID 178522253, compound

HRID 1179690Notes

Reaction equation

HRID 1179690 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=[O:8])=[CH:5][CH:4]=1.ClC1C=CC(C([NH:21][C:22]2[CH:23]=[N:24][C:25]([OH:28])=[CH:26][CH:27]=2)=O)=CC=1>>[OH:28][C:25]1[N:24]=[CH:23][C:22]([NH:21][C:7](=[O:8])[C:6]2[CH:10]=[CH:11][C:3]([C:2]([F:13])([F:12])[F:1])=[CH:4][CH:5]=2)=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 676074-(Trifluoromethyl)benzoyl chlorideHCID 178522254HCID 178522254, compound

Product 1

HCID 178522253HCID 178522253, compound

Procedure

Starting from 4-trifluoromethylbenzoyl chloride (2.09 g, 10.0 mmol) and using the procedure as described for the preparation of 4-Chloro-N-(6-hydroxy-pyridin-3-yl)-benzamide yielded the title compound, which was used without further purification.

Sources & evidence

ORD record
ord-af3dc3e7094648f1964f45393e163a3b
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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