Carbamic chloride, N-methyl-N-phenyl- → HCID 10287353, compound

HRID 1179702Notes

Reaction equation

HRID 1179702 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[CH:5][C:6]([O:9][C:10]2[CH:11]=[C:12]([OH:16])[CH:13]=[CH:14][CH:15]=2)=[N:7][CH:8]=1.[CH3:19][N:20]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:21](Cl)=[O:22]>ClCCl>[F:18][C:2]([F:1])([F:17])[C:3]1[CH:4]=[CH:5][C:6]([O:9][C:10]2[CH:11]=[C:12]([O:16][C:21](=[O:22])[N:20]([CH3:19])[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH:13]=[CH:14][CH:15]=2)=[N:7][CH:8]=1

Participants

4

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 220476983-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol

Product 1

HCID 10287353HCID 10287353, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared from 3-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to flash chromatography (Quad flash 25, dichlormethane) (89%, oil). HPLC-MS m/z=389.1 (M+1), Rt: 5.08 min.

Sources & evidence

ORD record
ord-5117a82db7fc40318c1aea8106ed1caf
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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