Carbamic chloride, N-methyl-N-phenyl- → HCID 10215997, compound

HRID 1179703Notes

Reaction equation

HRID 1179703 reaction equation
[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[CH3:17][N:18]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:19](Cl)=[O:20]>>[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][C:19](=[O:20])[N:18]([CH3:17])[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 6208804-(3,5-Dichloro-pyridin-2-yloxy)-phenol

Product 1

HCID 10215997HCID 10215997, compound

Procedure

The title compound was prepared from 4-(3,5-dichloro-pyridin-2-yloxy)-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was purified by preparative HPLC (53%, crystals). HPLC-MS m/z=389.1 (M+1), Rt: 5.1 min.

Workup

  1. customThe crude product was purified by preparative HPLC (53%, crystals)

Sources & evidence

ORD record
ord-669ea595b2bb473c954da31aa5b1ad92
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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