Carbamic chloride, N-methyl-N-phenyl- → HCID 69517854, compound

HRID 1179707Notes

Reaction equation

HRID 1179707 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[O:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1.[CH3:19][N:20]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:21](Cl)=[O:22]>>[F:1][C:2]([F:17])([F:18])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[O:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][C:21](=[O:22])[N:20]([CH3:19])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 12940614HCID 12940614, compound

Product 1

HCID 69517854HCID 69517854, compound

Procedure

The title compound was prepared from 4-(3-trifluoromethyl-phenoxy)-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was purified by preparative HPLC (73%, white crystals). HPLC-MS m/z=388.2 (M+1), Rt: 5.37 min.

Workup

  1. customThe crude product was purified by preparative HPLC (73%, white crystals)

Sources & evidence

ORD record
ord-b5e185b202fb49bab4516d1f1be59772
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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