Carbamic chloride, N-methyl-N-phenyl- → HCID 10196589, compound

HRID 1179709Notes

Reaction equation

HRID 1179709 reaction equation
[C:1]1([S:7]([C:10]2[CH:15]=[C:14]([O:16][C:17]3[C:22]([Cl:23])=[CH:21][C:20]([C:24]([F:27])([F:26])[F:25])=[CH:19][N:18]=3)[CH:13]=[CH:12][C:11]=2[OH:28])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:29][N:30]([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[C:31](Cl)=[O:32]>>[C:1]1([S:7]([C:10]2[CH:15]=[C:14]([O:16][C:17]3[C:22]([Cl:23])=[CH:21][C:20]([C:24]([F:27])([F:26])[F:25])=[CH:19][N:18]=3)[CH:13]=[CH:12][C:11]=2[O:28][C:31](=[O:32])[N:30]([CH3:29])[C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 1473922HCID 1473922, compound

Product 1

HCID 10196589HCID 10196589, compound

Procedure

The title compound was prepared from 2-benzenesulfonyl-4-(3-chloro-5-trifluoromethyl-pyridine-2-yloxy)-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was purified by preparative HPLC (68%, white crystals). HPLC-MS m/z=563.1 (M+1), Rt: 5.3 min.

Workup

  1. customThe crude product was purified by preparative HPLC (68%, white crystals)

Sources & evidence

ORD record
ord-0d01105a9eb54546935ce13b7d74a2e3
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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