7-Hydroxy-3-(4-methoxyphenyl)-4-methyl-2H-1-benzopyran-2-one → Methyl-phenyl-carbamic Acid 3-(4-methoxy-phenyl)-4-methyl-2-oxo-2H-chromen-7-yl Ester

HRID 1179739Notes

Reaction equation

HRID 1179739 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH3:21])=[C:7]([C:13]3[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=3)[C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1.[I-].C[N+]1C=CN([C:29](=[O:38])[N:30]([CH3:37])[C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)C=1>>[CH3:20][O:19][C:16]1[CH:17]=[CH:18][C:13]([C:7]2[C:8](=[O:12])[O:9][C:10]3[C:5]([C:6]=2[CH3:21])=[CH:4][CH:3]=[C:2]([O:1][C:29](=[O:38])[N:30]([CH3:37])[C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:11]=3)=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 53576277-Hydroxy-3-(4-methoxyphenyl)-4-methyl-2H-1-benzopyran-2-oneHCID 109478841-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide

Product 1

HCID 10287776Methyl-phenyl-carbamic Acid 3-(4-methoxy-phenyl)-4-methyl-2-oxo-2H-chromen-7-yl EsterYield 43.3%

Procedure

The title compound (90 mg, 43% yield, white solid) was prepared from 7-hydroxy-3-(4-methoxy-phenyl)-4-methyl-chromen-2-one (141 mg, 0.50 mmol) and 1-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide (175 mg, 0.51 mmol).

Sources & evidence

ORD record
ord-ecb0f7ac96424306ba4f728668bb92ff
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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