7-Hydroxy-4-methyl-3-phenyl-2H-1-benzopyran-2-one → Methyl-phenyl-carbamic Acid 4-methyl-2-oxo-3-phenyl-2H-chromen-7-yl Ester

HRID 1179740Notes

Reaction equation

HRID 1179740 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH3:19])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1.[I-].C[N+]1C=CN([C:27](=[O:36])[N:28]([CH3:35])[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)C=1>>[CH3:19][C:6]1[C:5]2[C:10](=[CH:11][C:2]([O:1][C:27](=[O:36])[N:28]([CH3:35])[C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:3][CH:4]=2)[O:9][C:8](=[O:12])[C:7]=1[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 53566287-Hydroxy-4-methyl-3-phenyl-2H-1-benzopyran-2-oneHCID 109478841-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide

Product 1

HCID 10309458Methyl-phenyl-carbamic Acid 4-methyl-2-oxo-3-phenyl-2H-chromen-7-yl EsterYield 62.3%

Procedure

The title compound (120 mg, 52% yield, white solid) was prepared from 7-hydroxy-4-methyl-3-phenyl-chromen-2-one (126 mg, 0.50 mmol) and 1-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide (175 mg, 0.51 mmol).

Sources & evidence

ORD record
ord-ef04661a3e4b41a38daa1cff84002424
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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