3-Benzyl-4-methylumbelliferone → 3,4-Dihydro-2H-quinoline-1-carboxylic Acid 3-benzyl-4-methyl-2-oxo-2H-chromen-7-yl Ester

HRID 1179764Notes

Reaction equation

HRID 1179764 reaction equation
[CH2:1]([C:8]1[C:9](=[O:20])[O:10][C:11]2[C:16]([C:17]=1[CH3:18])=[CH:15][CH:14]=[C:13]([OH:19])[CH:12]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I-].[N:22]1([C:32](N2C=C[N+](C)=C2)=[O:33])[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH2:25][CH2:24][CH2:23]1>>[CH2:1]([C:8]1[C:9](=[O:20])[O:10][C:11]2[C:16]([C:17]=1[CH3:18])=[CH:15][CH:14]=[C:13]([O:19][C:32]([N:22]1[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[CH2:25][CH2:24][CH2:23]1)=[O:33])[CH:12]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 53385383-Benzyl-4-methylumbelliferoneHCID 10959576HCID 10959576, compound

Product 1

HCID 865891933,4-Dihydro-2H-quinoline-1-carboxylic Acid 3-benzyl-4-methyl-2-oxo-2H-chromen-7-yl Ester

Procedure

The title compound was prepared from 3-benzyl-7-hydroxy-4-methyl-2H-chromen-2-one and 3-(3,4-dihydro-2H-quinoline-1-carbonyl)-1-methyl-3H-imidazol-1-ium iodide. HPLC-MS m/z=426 (M+1), Rt: 5.34 min.

Sources & evidence

ORD record
ord-62e46a8ce2fb443dbd8a95c270646be5
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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