7-Hydroxy-4-methyl-3-phenyl-2H-1-benzopyran-2-one → 3,4-Dihydro-2H-quinoline-1-carboxylic acid 4-methyl-2-oxo-3-phenyl-2H-chromen-7-yl Ester

HRID 1179770Notes

Reaction equation

HRID 1179770 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH3:19])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1.[I-].[N:21]1([C:31](N2C=C[N+](C)=C2)=[O:32])[C:30]2[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH2:24][CH2:23][CH2:22]1>>[CH3:19][C:6]1[C:5]2[C:10](=[CH:11][C:2]([O:1][C:31]([N:21]3[C:30]4[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=4)[CH2:24][CH2:23][CH2:22]3)=[O:32])=[CH:3][CH:4]=2)[O:9][C:8](=[O:12])[C:7]=1[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 53566287-Hydroxy-4-methyl-3-phenyl-2H-1-benzopyran-2-oneHCID 109595761-(3,4-Dihydroquinolin-1(2H)-ylcarbonyl)-3-methyl-1H-imidazol-3-ium Iodide

Product 1

HCID 865891993,4-Dihydro-2H-quinoline-1-carboxylic acid 4-methyl-2-oxo-3-phenyl-2H-chromen-7-yl EsterYield 73%

Procedure

The title compound (150 mg, 73% yield, white solid) was prepared from 7-hydroxy-4-methyl-3-phenyl-chromen-2-one (126 mg, 0.50 mmol) and 3-(3,4-dihydro-2H-quinoline-1-carbonyl)-1-methyl-3H-imidazol-1-ium iodide (188 mg, 0.51 mmol).

Sources & evidence

ORD record
ord-589e32a27eb74bbbbbea0bd8bedc10d1
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

Loading…