4-Morpholinecarbonyl chloride → HCID 10150335, compound

HRID 1179774Notes

Reaction equation

HRID 1179774 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:16])[C:7]=1[O:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=1.[N:17]1([C:23](Cl)=[O:24])[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[Cl:16][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[O:8][C:9]1[CH:10]=[CH:11][C:12]([O:15][C:23]([N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)=[O:24])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 27265874-[(3,5-Dichloro-4-pyridinyl)oxy]phenol

Product 1

HCID 10150335HCID 10150335, compound

Procedure

The title compound was prepared from 4-(3,5-dichloro-pyridin-4-yloxy)-phenol and morpholine-4-carbonyl chloride. The crude product was purified by preparative HPLC (66%, white crystals. HPLC-MS m/z=368.9 (M+1), Rt: 4.0 min.

Workup

  1. customThe crude product was purified by preparative HPLC (66%, white crystals

Sources & evidence

ORD record
ord-efe6ce4021164b7fb6245eba4599bdb8
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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