4-Morpholinecarbonyl chloride → HCID 69520276, compound

HRID 1179775Notes

Reaction equation

HRID 1179775 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:16]=[CH:15][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.[N:19]1([C:25](Cl)=[O:26])[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[F:1][C:2]([F:17])([F:18])[C:3]1[CH:16]=[CH:15][C:6]([O:7][C:8]2[CH:9]=[CH:10][C:11]([O:14][C:25]([N:19]3[CH2:24][CH2:23][O:22][CH2:21][CH2:20]3)=[O:26])=[CH:12][CH:13]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 170230p-(4-(Trifluoromethyl)phenoxy)phenol

Product 1

HCID 69520276HCID 69520276, compound

Procedure

The title compound was prepared from 4-(4-trifluoromethyl-phenoxy)-phenol and morpholine-4-carbonyl chloride. The crude product was purified by preparative HPLC (74%, white crystals). HPLC-MS m/z=368.1 (M+1), Rt: 4.85 min.

Workup

  1. customThe crude product was purified by preparative HPLC (74%, white crystals)

Sources & evidence

ORD record
ord-67ae39f10c0d41d398961c76199b4db9
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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