HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid 3-(4-methoxy-phenyl)-pyrazol-1-yl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamic chloride, N-methyl-N-phenyl- | HCID 77969 | — |
| Reactant | 1-Hydroxy-3-(4-methoxyphenyl)pyrazole | HCID 11805519 | — |
| Solvent | Ethylacetate heptane | HCID 21899848 | — |
| Product | Methyl-phenyl-carbamic Acid 3-(4-methoxy-phenyl)-pyrazol-1-yl Ester | HCID 10236710 | — |
Reaction Steps
The title compound was prepared from 1-hydroxy-3-(4-methoxyphenyl)pyrazole and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to flash chromatography (Quad flash 25, EtOAc-heptane) (93%, oil). HPLC-MS m/z=346.1 (M+Na), Rt: 4.21 min. δH(300 MHz; CDCl3): 3.45 (bs, 3H), 3.84 (s, 3H), 6.50 (d, 1H), 6.91 (d, 2H), 7.30-7.48 (m, 6H), 7.70 (d, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279470B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-3e399edd618943819430f8fb68d273d3 |
| Source note | uspto-grants-2007_10 |