Carbamic chloride, N-methyl-N-phenyl- → HCID 69518990, compound

HRID 1179806Notes

Reaction equation

HRID 1179806 reaction equation
[OH:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH3:11][N:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:13](Cl)=[O:14]>>[CH3:11][N:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:13]([N:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=[C:2]1[O:1][C:13](=[O:14])[N:12]([CH3:11])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:14]

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 178517141HCID 178517141, compound

Product 1

HCID 69518990HCID 69518990, compound

Procedure

The title product was prepared from 2-hydroxybenzimidazole and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC. (14%, white crystals). HPLC-MS: m/z=401.2 (M+1); Rt: 3.88 min, purity: 83%.

Sources & evidence

ORD record
ord-d0d0c23920214003b106f041e434268f
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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