Carbamic chloride, N-methyl-N-phenyl- → HCID 69519242, compound

HRID 1179807Notes

Reaction equation

HRID 1179807 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:16])[C:10]2[CH:15]=[CH:14][CH:13]=[N:12][CH:11]=2)=[CH:4][CH:3]=1.[CH3:17][N:18]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:19](Cl)=[O:20]>>[N:12]1[CH:13]=[CH:14][CH:15]=[C:10]([C:9]([NH:8][C:5]2[CH:4]=[CH:3][C:2]([O:1][C:19](=[O:20])[N:18]([CH3:17])[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:7][CH:6]=2)=[O:16])[CH:11]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 571860HCID 571860, compound

Product 1

HCID 69519242HCID 69519242, compound

Procedure

The title product was prepared from N-(4-Hydroxy-phenyl)-nicotinamide and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC. (1%, light yellow crystals). HPLC-MS: m/z=348.1 (M+1); Rt: 2.96 min.

Sources & evidence

ORD record
ord-abc5c1c8eef54070b43e7697de274b54
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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