Carbamic chloride, N-methyl-N-phenyl- → HCID 69518123, compound

HRID 1179813Notes

Reaction equation

HRID 1179813 reaction equation
[OH:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]([N:8]2[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH2:9]2)=[O:7])=[CH:4][CH:3]=1.[CH3:17][N:18]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:19](Cl)=[O:20]>>[CH3:14][N:11]1[CH2:10][CH2:9][N:8]([C:6]([C:5]2[CH:15]=[CH:16][C:2]([O:1][C:19](=[O:20])[N:18]([CH3:17])[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:3][CH:4]=2)=[O:7])[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 4740811(4-Hydroxyphenyl)(4-methylpiperazin-1-yl)methanone

Product 1

HCID 69518123HCID 69518123, compound

Procedure

The title product was prepared from 1-(4-hydroxybenzoyl)-4-methyl-piperazine and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC (22%, colorless oil). HPLC-MS: m/z=354.1 (M+1); Rt: 2.07 min.

Sources & evidence

ORD record
ord-f48307cd69cc43fcbec6b6c80d7b2619
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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