Carbamic chloride, N-methyl-N-phenyl- → HCID 69516933, compound

HRID 1179827Notes

Reaction equation

HRID 1179827 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH3:16])[C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[O:10])=[CH:4][CH:3]=1.[CH3:17][N:18]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:19](Cl)=[O:20]>>[CH3:16][N:8]([C:9]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)=[O:10])[C:5]1[CH:4]=[CH:3][C:2]([O:1][C:19](=[O:20])[N:18]([CH3:17])[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 3713660HCID 3713660, compound

Product 1

HCID 69516933HCID 69516933, compound

Procedure

The title product was prepared from thiophene-2-carboxylic acid (4-hydroxy-phenyl)-methyl-amide and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC (16%, oil). HPLC-MS: m/z=367.2 (M+1); Rt: 3.97 min.

Sources & evidence

ORD record
ord-0f1d63dec05148cfabbe16e2cd65eb47
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

Loading…