Tetrahydrofurfurylamine → Methyl-phenyl-carbamic Acid 4-[(tetrahydro-furan-2-ylmethyl)-carbamoyl]-phenyl Ester

HRID 1179844Notes

Reaction equation

HRID 1179844 reaction equation
O=C1CCC(=O)N1O[C:9](=[O:27])[C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17](=[O:26])[N:18]([CH3:25])[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:12][CH:11]=1.[O:28]1[CH2:32][CH2:31][CH2:30][CH:29]1[CH2:33][NH2:34]>>[O:28]1[CH2:32][CH2:31][CH2:30][CH:29]1[CH2:33][NH:34][C:9]([C:10]1[CH:11]=[CH:12][C:13]([O:16][C:17](=[O:26])[N:18]([CH3:25])[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:14][CH:15]=1)=[O:27]

Participants

3

Reactant 2

HCID 253298TetrahydrofurfurylamineHCID 865892064-(Methyl-phenyl-carbamoyloxy)-benzoic Acid 2,5-dioxo-pyrrolidin-1-yl Ester

Product 1

HCID 69517656Methyl-phenyl-carbamic Acid 4-[(tetrahydro-furan-2-ylmethyl)-carbamoyl]-phenyl Ester

Procedure

The title product was prepared from 4-(methyl-phenyl-carbamoyloxy)-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester and C-(tetrahydro-furan-2-yl)methylamine. The crude product was used without further purification (86%, oil). HPLC-MS: m/z=(M+1); Rt: min.

Workup

  1. customThe crude product was used without further purification (86%, oil)

Sources & evidence

ORD record
ord-0a89c7ee0ce6406dbad3e2f84fd0c860
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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