1-(2-Chlorophenyl)piperazine → HCID 69518959, compound

Participants

Reaction Steps

The the hydrochloride of title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate and 1-(2-chlorophenyl)piperazine. Drying in vacuo at 50° C. for 3½ h gave the title compound; 1H NMR (DMSO-d6): δ8.61-8.55 (br, 1H), 8.29-8.20 (dd-like, 1H), 7.53-7.41 (m, 1H), 7.39-7.17 (m, 7H), 7.14-7.03 (m, 1H), 4.58 (br s, NH+water), 3.85-3.55 (br m, 4H), 3.12-2.99 (br m, 4H); HPLC-MS: m/z=478 (M+H); IR (KBr): ν 1733 (C═O) cm−1.

Provenance & Evidence