4-Morpholinecarbonyl chloride → HCID 69517476, compound

HRID 1179918Notes

Reaction equation

HRID 1179918 reaction equation
Cl.[OH:2][N:3]1[CH:7]=[CH:6][N:5]=[C:4]1[Br:8].[N:9]1([C:15](Cl)=[O:16])[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1>>[Br:8][C:4]1[N:3]([O:2][C:15]([N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[O:16])[CH:7]=[CH:6][N:5]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 131725815HCID 131725815, compound

Product 1

HCID 69517476HCID 69517476, compound

Procedure

The title compound was prepared from 1-hydroxy-2-bromoimidazole, hydrochloride and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc) (98%, crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc) (98%, crystals)

Sources & evidence

ORD record
ord-cfd07cc7445e4af9a0c61995edeb2221
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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