4-Morpholinecarbonyl chloride → HCID 69519760, compound

HRID 1179923Notes

Reaction equation

HRID 1179923 reaction equation
[OH:1][N:2]1[CH:6]=[C:5]([I:7])[CH:4]=[N:3]1.[N:8]1([C:14](Cl)=[O:15])[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1>>[I:7][C:5]1[CH:4]=[N:3][N:2]([O:1][C:14]([N:8]2[CH2:13][CH2:12][O:11][CH2:10][CH2:9]2)=[O:15])[CH:6]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 133912504-Iodo-1H-pyrazol-1-ol

Product 1

HCID 69519760HCID 69519760, compound

Procedure

The title compound was prepared from 1-hydroxy-4-iodopyrazole and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (99%, crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (99%, crystals)

Sources & evidence

ORD record
ord-969f02a9a1604142848ca805e6dadb2a
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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