4-Morpholinecarbonyl chloride → HCID 69517474, compound

HRID 1179924Notes

Reaction equation

HRID 1179924 reaction equation
[OH:1][N:2]1[C:6]([Br:7])=[C:5]([Br:8])[C:4]([Br:9])=[N:3]1.[N:10]1([C:16](Cl)=[O:17])[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1>>[Br:9][C:4]1[C:5]([Br:8])=[C:6]([Br:7])[N:2]([O:1][C:16]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[O:17])[N:3]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 133912563,4,5-Tribromo-1H-pyrazol-1-ol

Product 1

HCID 69517474HCID 69517474, compound

Procedure

The title compound was prepared from 1-hydroxy-3,4,5-tribromopyrazole and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (90%, crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (90%, crystals)

Sources & evidence

ORD record
ord-b96d23ba9a9645c0874e0aee75dcdda7
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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