4-Morpholinecarbonyl chloride → HCID 45091616, compound

HRID 1179927Notes

Reaction equation

HRID 1179927 reaction equation
[OH:1][N:2]1[CH:6]=[CH:5][CH:4]=[N:3]1.[N:7]1([C:13](Cl)=[O:14])[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1>>[N:2]1([O:1][C:13]([N:7]2[CH2:12][CH2:11][O:10][CH2:9][CH2:8]2)=[O:14])[CH:6]=[CH:5][CH:4]=[N:3]1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 30167331-hydroxy-1H-pyrazole

Product 1

HCID 45091616HCID 45091616, compound

Procedure

The title compound was prepared from 1-hydroxypyrazole and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (94%, crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (94%, crystals)

Sources & evidence

ORD record
ord-f9a5cf59a2ce40cab7f2f8af2bfcf181
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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