2,4-difluoro-N-methylaniline → HCID 69518150, compound

HRID 1179998Notes

Reaction equation

HRID 1179998 reaction equation
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[NH:4][CH3:5].Cl[C:12]([O:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][C:22]2[CH:27]=[CH:26][C:25]([C:28]([F:31])([F:30])[F:29])=[CH:24][N:23]=2)=[CH:17][CH:16]=1)=[O:13]>>[F:29][C:28]([F:31])([F:30])[C:25]1[CH:26]=[CH:27][C:22]([O:21][C:18]2[CH:19]=[CH:20][C:15]([O:14][C:12](=[O:13])[N:4]([C:3]3[CH:6]=[CH:7][C:8]([F:10])=[CH:9][C:2]=3[F:1])[CH3:5])=[CH:16][CH:17]=2)=[N:23][CH:24]=1

Participants

3

Reactant 2

HCID 27370232,4-difluoro-N-methylanilineHCID 220477624-(5-Trifluoromethylpyridin-2-yloxy)-phenyl chloroformate

Product 1

HCID 69518150HCID 69518150, compound

Procedure

The title product was prepared from 2,4-difluoro-N-methylaniline and 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate, preparative HPLC (method C) (37%, white crystals). HPLC-MS m/z=425.1 (M+1), Rt: 4.90 min.

Sources & evidence

ORD record
ord-91407e169b8e47e3a7140e8b4a03e890
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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