N-methyl-2-(trifluoromethoxy)aniline → HCID 86589216, compound

HRID 1179999Notes

Reaction equation

HRID 1179999 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[O:9][C:10]([F:13])([F:12])[F:11].Cl[C:15]([O:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][C:25]2[CH:30]=[CH:29][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:27][N:26]=2)=[CH:20][CH:19]=1)=[O:16]>>[F:32][C:31]([F:34])([F:33])[C:28]1[CH:29]=[CH:30][C:25]([O:24][C:21]2[CH:22]=[CH:23][C:18]([O:17][C:15](=[O:16])[N:2]([CH3:1])[C:3]3[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=3[O:9][C:10]([F:11])([F:12])[F:13])=[CH:19][CH:20]=2)=[N:26][CH:27]=1

Participants

3

Reactant 2

HCID 2775548N-methyl-2-(trifluoromethoxy)anilineHCID 220477624-(5-Trifluoromethylpyridin-2-yloxy)-phenyl chloroformate

Product 1

HCID 86589216HCID 86589216, compound

Procedure

The title product was prepared from N-methyl-2-(trifluoromethoxy)-aniline and 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate, preparative H PLC (method C) (49%, colourless oil). HPLC-MS m/z=473.2 (M+1), Rt: 5.18 min.

Sources & evidence

ORD record
ord-9170ebb4f0654c9a85aeceb7fc288312
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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