2-(4-Chlorophenyl)ethylamine → HCID 69518646, compound

HRID 1180005Notes

Reaction equation

HRID 1180005 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH2:10])=[CH:4][CH:3]=1.O=C1CCC(=O)N1[O:18][C:19](=O)[C:20]1[CH:25]=[CH:24][C:23]([O:26][C:27](=[O:36])[N:28]([CH3:35])[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[CH:22][CH:21]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH:10][C:19]([C:20]2[CH:25]=[CH:24][C:23]([O:26][C:27](=[O:36])[N:28]([CH3:35])[C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)=[CH:22][CH:21]=2)=[O:18])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 674302-(4-Chlorophenyl)ethylamineHCID 865892064-(Methyl-phenyl-carbamoyloxy)-benzoic Acid 2,5-dioxo-pyrrolidin-1-yl Ester

Product 1

HCID 69518646HCID 69518646, compound

Procedure

The title product was prepared from 2-(4-chloro-phenyl)-ethylamine and 4-(methyl-phenyl-carbamoyloxy)-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester. The crude product was subjected to preparative HPLC (method C) (39%, off-white crystals). HPLC-MS m/z=409.2 (M+1), Rt: 4.27 min.

Sources & evidence

ORD record
ord-220f3a1707504afe9cd3a2ca5f21a7ad
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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