HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)phenylboronic acid → Methyl-phenyl-carbamic Acid 4'-trifluoromethyl-biphenyl-4-yl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Reactant | Methyl-phenyl-carbamic Acid 4-iodo-phenyl Ester | HCID 69517304 | — |
| Product | Methyl-phenyl-carbamic Acid 4'-trifluoromethyl-biphenyl-4-yl Ester | HCID 69519615 | — |
Reaction Steps
The title compound was prepared from methyl-phenyl-carbamic acid 4-iodo-phenyl ester and 4-trifluoromethylphenylboronic acid. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane 1:9) (42%, light brown crystals).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279470B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-e3becde912d04f959c850606570f1341 |
| Source note | uspto-grants-2007_10 |