3-Pyridinylboronic acid → Methyl-phenyl-carbamic Acid 4-pyridin-3-yl-phenyl Ester

HRID 1180030Notes

Reaction equation

HRID 1180030 reaction equation
I[C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:18])[N:10]([CH3:17])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:4][CH:3]=1.[N:19]1[CH:24]=[CH:23][CH:22]=[C:21](B(O)O)[CH:20]=1>>[N:19]1[CH:24]=[CH:23][CH:22]=[C:21]([C:2]2[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:18])[N:10]([CH3:17])[C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:4][CH:3]=2)[CH:20]=1

Participants

3

Reactant 2

HCID 27343783-Pyridinylboronic acidHCID 69517304Methyl-phenyl-carbamic Acid 4-iodo-phenyl Ester

Product 1

HCID 69519349Methyl-phenyl-carbamic Acid 4-pyridin-3-yl-phenyl Ester

Procedure

The title compound was prepared from methyl-phenyl-carbamic acid 4-iodo-phenyl ester and pyridine-3-boronic acid. The crude product was purified by preparative HPLC (Gilson) (5%, brown oil).

Workup

  1. customThe crude product was purified by preparative HPLC (Gilson) (5%, brown oil)

Sources & evidence

ORD record
ord-5cd6b593ee764b7cab1ffde5d946bb53
Source dataset
uspto-grants-2007_10
Patent number
US07279470B2

Reaction notes

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