Acetaldehyde → HCID 69518612, compound

HRID 1180042Notes

Reaction equation

[C:1]1([CH3:30])[CH:6]=[CH:5][C:4]([S:7]([NH:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][C:16]([O:19][C:20](=[O:29])[N:21]([CH3:28])[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:15][CH:14]=2)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[CH:31](=O)[CH3:32].C=O>>[CH3:31][CH:32]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:19][C:20](=[O:29])[N:21]([CH3:28])[C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:17]=2)[CH2:12][CH2:11][N:10]1[S:7]([C:4]1[CH:3]=[CH:2][C:1]([CH3:30])=[CH:6][CH:5]=1)(=[O:8])=[O:9]

Participants

Reactant 3

HCID 177Acetaldehyde

HCID 712Formaldehyde

HCID 69517870HCID 69517870, compound

Product 1

HCID 69518612HCID 69518612, compound

Procedure

The title compound was prepared using methyl-phenyl-carbamic acid 4-[2-(toluene-4-sulfonylamino)-ethyl]-phenyl ester as the sulfonamide and acetaldehyde in stead of formaldehyde. The crude product was purified by preparative HPLC (Gilson) (22%, brown oil).

Workup

customThe crude product was purified by preparative HPLC (Gilson) (22%, brown oil)

Sources & evidence

ORD record: ord-162a239261f64228a8f429ea72be4a84
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07279470B2

Reaction notes

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