Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180057Generated: November 3, 2026

Trifluoroacetic acid → Methyl-phenyl-carbamic acid 4-[2-(imidazol-1-yloxy)-ethyl]-phenyl ester

https://huagongshe.com/reaction/1180057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant1-hydroxyimidazole HydrochlorideHCID 10313128—
ReactantMethyl-phenyl-carbamic Acid 4-(2-hydroxy-ethyl)-phenyl EsterHCID 69520342—
ProductMethyl-phenyl-carbamic acid 4-[2-(imidazol-1-yloxy)-ethyl]-phenyl esterHCID 6951766979%

Reaction Steps

The title compound was prepared as its TFA salt in 79% yield as an oil using methyl-phenyl-carbamic acid 4-(2-hydroxy-ethyl)-phenyl ester and 1-hydroxyimidazole hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07279470B2
Source datasetuspto-grants-2007_10
ORD IDord-8cc4b67bf52c47b690ff3fed7eadd142
Source noteuspto-grants-2007_10