HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-6-fluorobenzonitrile → 3,2'-Difluoro-5'-nitrobiphenyl-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-6-fluorobenzonitrile | HCID 2783139 | — |
| Reactant | 2-Fluoro-5-nitrophenylboronic acid, pinacol ester | HCID 3833297 | — |
| Product | 3,2'-Difluoro-5'-nitrobiphenyl-2-carbonitrile | HCID 22285282 | — |
Reaction Steps
2-Bromo-6-fluorobenzonitrile and 2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane were coupled following the procedure in Example 2 to afford 3,2′-difluoro-5′-nitrobiphenyl-2-carbonitrile as a black solid: δH (360 MHz, CDCl3) 7.32-7.44 (3H, m), 7.71-7.77 (1H, m), 8.35-8.41 (2H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279580B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-1dd79d2c08344148bd1725d969ac912b |
| Source note | uspto-grants-2007_10 |