HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenylboronic acid → HCID 10452918, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Reactant | 2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-alpha]pyridin-7-yl]propan-2-ol | HCID 67486680 | — |
| Product | HCID 10452918 | HCID 10452918 | 10% |
Reaction Steps
2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]-propan-2-ol and 4-cyanobenzeneboronic acid were coupled in the same way as in Example 30 to give 2′-fluoro-5′-[8-fluoro-7-(1-hydroxy-1-methylethyl)-imidazo[1,2-α]pyridin-3-yl]biphenyl-4-carbonitrile as an off-white solid (12 mg, 10%): m/z (ES+) 390 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279580B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-e2fcd201db03477c815a17d18219309b |
| Source note | uspto-grants-2007_10 |