HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluoro-2-methoxyphenyl)boronic acid → HCID 10251101, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluoro-2-methoxyphenyl)boronic acid | HCID 2782672 | — |
| Reactant | 2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-alpha]pyridin-7-yl]propan-2-ol | HCID 67486680 | — |
| Product | HCID 10251101 | HCID 10251101 | 4% |
Reaction Steps
2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]-propan-2-ol and 4-fluoro-2-methoxybenzeneboronic acid were coupled in the same way as in Example 30 to give 2-[3-(2,4′-difluoro-2′-methoxy-biphenyl-5-yl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]propan-2-ol as an off-white solid (5 mg, 4%): m/z (ES+) 413 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07279580B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-a1837ae02fdb4c2ca9de228a531feb95 |
| Source note | uspto-grants-2007_10 |