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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180314Generated: November 1, 2026

2-Methoxyphenylboronic acid → HCID 10318465, compound

https://huagongshe.com/reaction/1180314

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxyphenylboronic acidHCID 2733958—
Reactant2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-alpha]pyridin-7-yl]propan-2-olHCID 67486680—
ProductHCID 10318465HCID 10318465—

Reaction Steps

2-[3-(3-Chloro-4-fluorophenyl)-8-fluoroimidazo[1,2-α]pyridin-7-yl]-propan-2-ol and 2-methoxybenzeneboronic acid were coupled in the same way as in Example 30 to give 2-[8-fluoro-3-(2-fluoro-2′-methoxybiphenyl-5-yl)imidazo[1,2-α]pyridin-7-yl]propan-2-ol as an off-white solid (8 mg; 7%): m/z (ES+) 395 [MH+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07279580B2
Source datasetuspto-grants-2007_10
ORD IDord-5f7eb49a6ace46e79c72e228ccff8c9d
Source noteuspto-grants-2007_10