Tetrabutylammonium Fluoride → HCID 136338597, compound

Participants

Reaction Steps

The title compound was prepared by reacting 4′-{[tert-butyl(dimethyl)silyl]oxy}-2-fluoro-[1,1′-biphenyl]-4-carbaldehyde oxime (1.02 mmol) with tetrabutylammonium fluoride (1.12 mL of 1.0 M solution in tetrahydrofuran, 1.12 mmol) according to Method E to yield 198 mg (84%) of a white solid: mp 178-180° C.; 1H NMR (DMSO-d6): δ 6.84-6.89 (2H, m), 7.39-5.54 (5H, m), 8.17 (1H, s), 9.71 (1H, s), 11.43 (1H, s); MS (ESI) m/z 230 (M−H)−, 232 (M+H)+.

Provenance & Evidence