Hydroxyamine hydrochloride → HCID 136338599, compound

Participants

Reaction Steps

The title compound was prepared by reacting 2′-chloro-4′-(dibromomethyl)-1,1′-biphenyl-4-ol (270 mg, 0.722 mmol) with hydroxylamine hydrochloride (185 mg, 2.66 mmol) according to Method C to yield 160 mg (90%) of white solid: mp 178-179° C.; 1H NMR (DMSO-d6): δ 6.85 (2H, d, J=8.54 Hz), 7.28 (2H, d, J=8.51 Hz), 7.39 (1H, d, J=7.98 Hz), 7.60 (1H, dd, J=7.65 Hz, J=1.42 Hz), 7.72 (1H, d, J=1.34 Hz), 8.18 (1H, s), 9.67 (1H, s), 11.45 (1H, s); MS (ESI) m/z 246/248 (M−H)−.

Provenance & Evidence