Hydroxyamine hydrochloride → HCID 136338604, compound

Participants

Reaction Steps

The title compound was prepared by reacting 3,5-dichloro-4′-hydroxy-1,1′-biphenyl-4-carbaldehyde (170 mg, 0.637 mmol) with hydroxylamine hydrochloride (89 mg, 1.27 mmol) according to Method F to yield 160 mg (89%) of a white solid: mp 183-186° C.; 1H NMR (DMSO-d6): δ 6.86 (2H, d, J=8.79 Hz), 7.63 (2H, d, J=8.79 Hz), 7.76 (2H, s), 8.25 (1H, s), 9.81 (1H, s), 11.78 (1H, s); MS (ESI) m/z 280/282/284 (M−H)−, 282/284/286 (M+H)+.

Provenance & Evidence