Potassium Hydroxide → HCID 69471369, compound

HRID 1180404Notes

Reaction equation

HRID 1180404 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:19]2[S:20][CH:21]=[CH:22][N:23]=2)[O:9][CH:10]([CH2:15][CH:16]([CH3:18])[CH3:17])[C:11]([O:13]C)=[O:12])=[CH:4][CH:3]=1.[OH-].[K+:25]>>[K+:25].[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:19]2[S:20][CH:21]=[CH:22][N:23]=2)[O:9][CH:10]([CH2:15][CH:16]([CH3:17])[CH3:18])[C:11]([O-:13])=[O:12])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 69472556HCID 69472556, compound

Product 1

HCID 69471369HCID 69471369, compound

Procedure

Using the same protocol as described in example 17, step 5, methyl 2-[(4-bromophenyl)(1,3-thiazol-2-yl)methoxy]-4-methylpentanoate from step 2 (441 mg, 1.11 mmol) was hydrolysed with potassium hydroxide. The solid residue obtained was used as such in the next step.

Workup

  1. customThe solid residue obtained

Sources & evidence

ORD record
ord-45dd58730ee647dc8c83dbe0ea6f7582
Source dataset
uspto-grants-2007_10
Patent number
US07279478B2

Reaction notes

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