Methyl iodide → HCID 69473245, compound

Participants

Reaction Steps

A solution of methyl (2S)-4-methyl-2-{[(R)-phenyl(4-pyridin-3-ylphenyl)methyl]oxy}pentanoate from example 36 step 2 (881 mg, 2.26 mmol) and iodomethane (3.2 g, 22.6 mmol) in acetonitrile (22 mL) was heated in a pressure tube immersed in an oil bath at 120° C. for 18 hours. The solution was concentrated and the residue pumped on to obtain the pyridinium iodide salt as a foam.

Provenance & Evidence